The following information is on the key interventions, policy decisions and strategies employed in Uganda between March 2020 and December 2021 for the response to COVID-19 and the maintenance of essential health services.

Exemplars in COVID-19 conceptual framework for assessing epidemic preparedness and response

Ugandan officials had started to coordinate the country’s pandemic response months before Uganda reported its first COVID-19 cases on March 21, 2020. At the end of January 2020, when the World Health Organization (WHO) declared COVID-19 a public health emergency of international concern, the Ugandan Ministry of Health (MoH) activated its Public Health Emergency Operations Centre (PHEOC). The PHEOC was established in 2013; since then, it has been the MoH’s “central focal point for organizing, coordinating, supporting, and managing all aspects of evidence-based public health emergency response efforts.”1,2

The MoH also established a multisectoral, multidisciplinary National COVID-19 Task Force chaired by the prime minister,3 whose members and subcommittees were responsible for coordinating Uganda’s pandemic preparedness activities. For instance, the Scientific Advisory Committee worked to ensure decision making based on evidence and data, and the Technical Inter-Sectoral Committee pushed for public enforcement of, and adherence to, official policies and guidelines.4

In March 2020, the National Task Force’s Incident Management Team published a COVID-19 Preparedness and Response Plan with five key objectives5:

  • To strengthen leadership, stewardship, and coordination of preparedness and response efforts for COVID-19
  • To develop country capacity for early detection, reporting, investigation, confirmation, and referral of suspected cases to designated isolation units
  • To raise public awareness on the risk factors for transmission, prevention, and control of COVID-19 and promote the infection prevention and control practices including water, sanitation, and hygiene (WASH) to mitigate spread of COVID-19
  • To develop capacity for case management and psychosocial support for COVID-19
  • To strengthen the social protection mechanisms and mitigate the impact of COVID-19 on vulnerable groups.

The COVID-19 Preparedness and Response Plan managed the key pillars of Uganda’s direct response to the COVID-19 pandemic, including coordination and oversight, surveillance and laboratory systems, case management, risk communication, community engagement, logistics, and the continuity of essential health services (EHS).3 It also activated and coordinated response teams for key pandemic response activities such as surveillance, contact tracing, and isolation in local districts nationwide, even before most had reported a single case of COVID-19.3

Uganda’s COVID-19 Scientific Advisory Committee:

Members of the National Task Force’s COVID-19 Scientific Advisory Committee, established early in 2020, included public health specialists, physicians, epidemiologists, immunologists, and researchers from Makerere University’s schools of public health, medicine, and statistics, the Medical Research Council, and the Uganda Virus Research Institute (UVRI). This committee collated, synthesized, reviewed, and interpreted emerging data, translating emerging information into dynamic, evidence-based policies for COVID-19 response that could account for rapidly changing global and local conditions.

Note that the principal investigator for this research, Dr. Rhoda Wanyenze, was a member of this committee.

On March 31, 2020, Uganda’s Parliament approved a supplementary COVID-19 response budget that included $30.7 million (104 billion Ugandan shillings) for the country’s health sector.6 Further funding came from partnerships with international agencies such as the World Bank (which approved a $300 million budget support loan in June 2020),7 the International Monetary Fund (which approved a $491.5 million disbursement to stabilize the Ugandan economy in May 2020),8 and the Asian Development Bank.9

Uganda’s president also established a National Response Fund for COVID-19 to collect private contributions for essential supplies, such as test kits and personal protective equipment (PPE), and for direct relief for the country’s most vulnerable people.10

Lab worker Jackie Nkamoga dresses for work at the Uganda Virus Research Institute (UVRI) in Entebbe, Uganda, on January 21, 2022.
Lab worker Jackie Nkamoga dresses for work at the Uganda Virus Research Institute (UVRI) in Entebbe, Uganda, on January 21, 2022.
© GATES ARCHIVE. © 2022-2023 Exemplars in Global Health. All rights reserved.

In response to the delta surge in the early part of 2021, authorities in Uganda developed a National Corona Virus Disease-2019 (COVID-19) Resurgence Plan to cover the period between June 2021 and June 2022.11  The new plan reintroduced COVID-19 control measures, including a lockdown, and restricted travel from high-risk countries.12  It updated interventions in all the key areas the previous plan covered. For instance, the new plan shifted focus to home-based care for COVID-19 patients instead of institutional case management, to make more efficient use of limited resources as case counts increased, and it proposed the establishment of new regional emergency operations centers to improve subnational pandemic response. (Unfortunately, resource constraints delayed operationalization.)

The Resurgence Plan also added a new area of focus—vaccine delivery, coverage, and outreach—and reemphasized that EHS maintenance is a key component of pandemic response.11

Government funding for COVID-19 research in Uganda

In Uganda, government funding for research increased during the COVID-19 pandemic. The Presidential Scientific Initiative on Epidemics and the Ministry of Science, Technology, and Innovation provided grants to scientists shaping the country’s policy response13, and Makerere University established 110 research and innovation projects aimed at exploring public health challenges associated with COVID-19.14

These projects yielded key innovations that changed the way providers can deliver health care on the ground. For example, in June 2020, scientists from Makerere University and Kiira Motors Corporation developed a medical ventilator that is affordable, portable, and operated by solar-charged batteries. It can be used in ambulances and rural health facilities where electricity may be unreliable.15

Uganda also implemented strategies to maintain EHS delivery as soon as flagging performance across EHS indicators made it clear that they were necessary.

National, governmental, and population-level measures 

Public health risk communication was a preexisting strength of the Ugandan health system.16 Officials could adapt previous approaches, such as from the national Pandemic Influenza Preparedness Plan, as they developed new plans for COVID-19 risk communication.

To deliver key messages about the pandemic to everyone in the nation, the MoH used traditional platforms such as newspapers, radio, television, and billboards, along with a designated website for COVID-19 updates,17  an official Twitter account,18  Facebook pages, and other social media platforms. These communications were designed to increase community awareness of key measures ordinary people could take to prevent COVID-19 infection. They shared the location of local testing facilities and their availability, and later included information about vaccines and vaccine delivery. They also communicated with the public about adjustments to EHS delivery, including critical services such as family planning, in the pandemic context.19

Official risk communication targeted at health workers helped ensure that updated guidelines and protocols reached the people who needed to see them. These communications were intended to help boost health workers’ confidence in their own safety and ensure the quality and continuity of urgent and essential health care.

A mural encouraging people to be safe during the COVID-19 pandemic Kampala, Uganda, on January 20, 2022.
A mural encouraging people to be safe during the COVID-19 pandemic Kampala, Uganda, on January 20, 2022.
© GATES ARCHIVE. © 2022-2023 Exemplars in Global Health. All rights reserved.

Public health and social measures (PHSMs, also known as nonpharmaceutical interventions) like social distancing and mobility restrictions were a critical part of Uganda’s early response to COVID-19. Officials acted swiftly to implement them in March and April 2020.20  

On March 18, 2020, even before Uganda reported its first COVID-19 case, President Yoweri Museveni closed the country’s airports and territorial borders, quarantined travelers when they arrived in the country, and suspended all mass gatherings—including worship services, concerts, rallies, and cultural gatherings. Shortly thereafter, officials suspended public transportation, restricted the use of private vehicles, and declared a nationwide curfew, prohibiting all movement between 7 p.m. and 6:30 a.m.21,22 The government also closed public places such as bars and restaurants. On April 1, 2020, a nationwide lockdown banned all forms of public and private transportation and closed all businesses except for essential supermarkets and pharmacies.23

Starting in March 2020, all educational institutions in Uganda closed. They remained closed for nearly two years—the longest pandemic school closures in the world.24

 

 

Authorities began to lift Uganda’s first national lockdown on May 21, 2020.25 In June 2021, as case counts surged, President Museveni introduced another partial lockdown. Some travel was banned, open markets were closed, and church services were suspended. Schools remained closed all along.26,27

By December 2021, Uganda had implemented nearly a dozen different PHSMs including suspending international flights and establishing isolation centers, land-border restrictions, curfews, mandatory quarantine for travelers, mask mandates, and more (see figure below).20

COVID-19 stringency index for Uganda and neighboring countries

Our World in Data

The PHSMs that Ugandan authorities implemented to control the spread of the COVID-19 pandemic in 2020 coincided with a sharp drop in mobility during the pandemic’s early months (see figure below). This likely limited COVID-19 transmission, but researchers believe it also limited commercial activity, decreasing incomes and reducing economic growth, and introduced supply- and demand-side barriers to EHS delivery.

 

 

School closures in Uganda during the COVID-19 pandemic

To control the spread of COVID-19 in school facilities and across the country, Uganda imposed the longest school closure in the world during the COVID-19 pandemic.28 Officials closed all the country’s schools, from primary schools to universities, on March 20, 2020; most remained closed until January 2022.29 When officials implemented the closures, they estimated that about 15 million students in all would be affected.30

However, as it did in countries around the world, the decision to close schools also carried negative consequences, including learning loss for students and job loss for teachers.31 In March and April of 2020, Ugandan officials acted to mitigate these adverse consequences, especially for students:

  • They published a Parent’s Boost Guide to Support Children’s Learning at Home, which included skill-building activities, schedules, and recommendations for parents of younger children.32  
  • They secured airtime on selected radio and television stations across the country so teachers could deliver lessons in subjects such as math, English, physics, biology, and chemistry to primary and secondary students learning from home.33
  • They created free self-study materials, offering them to the public.34 Officials promised to distribute print copies of these materials, including homework packages and pamphlets, where Uganda Broadcasting (UBC) TV and radio stations were inaccessible.35,36 They also made digital copies of the materials available to all.

Meanwhile, development partners such as UNICEF helped Uganda’s Ministry of Education plan for mitigating the impact of COVID-19 on teachers and the education sector more broadly.37 ,38,39

However, despite these planned interventions, researchers observed that removing children from their classrooms for such a long period did have negative consequences. Key informants reported that the time students spent on schoolwork was reduced, and planned curricula were distorted.

Before the pandemic, about 40% of primary schools and 60% of secondary schools in Uganda were private institutions, but in 2020 and 2021 many of these private schools closed altogether. 40 Some 3,500 primary schools and 832 secondary schools serving nearly 400,000 students were at risk of closing permanently.41 Though the government continued to pay the wages of teachers in public schools, many private school teachers were laid off without pay,42 and those who kept their jobs often saw their salaries drop.43

Only 65.3% of Ugandan homes have a radio. Just 21.8% have a TV set. And Ugandan households frequently experience electricity outages. For these reasons, researchers believe that the infrastructure officials established for remote learning had a minimal impact on continuity of access to education.44 For example, the government promised to supply radios to households, but ultimately officials in the country’s Parliament did not approve the expenditure.45  

Likewise, internet connectivity in Uganda is patchy and expensive, so many students were likely unable to access web-based curriculum materials.46,47 Among 427 students surveyed in one study, only 16.5% had access to online learning platforms; the rest were not in touch with their lecturers.48

These obstacles affected different students unequally. For example, one 2020 survey of 27 parents of children with disabilities (and 12 peer parents) reported that only about 20% had received some form of materials from school to continue learning at home. Only 10% were able to access educational television programming and newspaper pull-outs.49 Wealthier parents were able to hire former teachers to tutor their children50, and more educated parents may have been better prepared for home schooling themselves.

In general, pandemic school closures in Uganda may have widened the serious inequities that already existed in the country’s education system, both between schools and between students.51

 

On May 4, 2020, Uganda’s president required all Ugandans six years and older to wear face masks in public.52,53 Those not wearing masks were barred from entering public places, and the police were empowered to enforce this policy.54

Even with the enforcement efforts of police and security forces, researchers found that mask use was inconsistent (see figure below). The reasons behind low or inconsistent adherence to mask use varied over time and space, and may have included perceived threat of disease, availability, or social norms. According to a 2021 survey of people in the Greater Kampala Metropolitan Area, a majority sometimes or always wore a face mask inside and outside public spaces, but the authors concluded that officials still needed to “raise awareness about face mask wearing and its efficacy to prevent COVID-19 infection.”55

In Uganda, partnerships with nongovernmental organizations (NGOs), private companies, and foreign governments enabled health workers, facilities, and village health teams (VHTs) to obtain essential PPE. Enforcement of PHSMs also provided opportunities for increased domestic production of masks and other key protective and pharmaceutical goods.56

For instance, by April 2020 the Uganda National Bureau of Standards had certified 38 local companies—many of which had previously manufactured alcohol or other goods—to manufacture hand sanitizer.50,57 By January 2020, the bureau had certified nearly 140 companies manufacturing 182 brands of sanitizer. Some of these supplies were exported to neighboring countries.58

 

 

Indoor and outdoor mask mandates inspired high demand for disposable medical masks as well as cloth masks.49 To meet this demand, Ugandan textile producers such as Nyanza Textile Industries Limited and the National Enterprises Corporation (the industrial arm of the Ugandan army) began to produce them at scale.59Even at the local level, small-scale entrepreneurs produced and sold protective goods such as cloth masks.60,61 Entrepreneurs and donors also produced handwashing facilities for the public to use: for instance, teams of young people worked with an NGO in Kamwokya, Kampala, to build free “hands-off” handwashing facilities for local businesses.62,63

Aziz (r), a street vendor, sells masks in Kampala, Uganda, on January 20, 2022.
Aziz (r), a street vendor, sells masks in Kampala, Uganda, on January 20, 2022.
© GATES ARCHIVE. © 2022-2023 Exemplars in Global Health. All rights reserved.

 

Case study: Individual adherence to COVID-19 public health and social measures in Uganda

As part of a study on factors associated with COVID-19 vaccine uptake in Uganda, in March 2021 researchers surveyed more than 1,000 Ugandan adults from across the country on their adherence to PHSMs. Overall, just 10% of respondents adhered to all COVID-19 preventive guidelines.64 (An earlier online survey conducted during March and April 2020 had found higher levels of adherence to handwashing, wearing face masks, physical distancing, and hygiene associated with coughing and sneezing: at that time, 29% of 1,726 respondents reported that they complied with all four preventive measures.65 )

According to the March 2021 study, two-thirds of participants had attended a large gathering in the past two weeks. Nearly 90% practiced physical distancing at least some of the time, and almost all of the respondents reported wearing a mask at least some of the time. However, just 10% complied with all preventive guidelines all the time.57

The study found higher rates of adherence to PHSMs among people living in the central region of Uganda, among women, and among those with higher monthly income.57

A follow-up study of more than 1,100 adults in November 2021 found higher reported adherence to PHSMs. Overall adherence was nearly 15%, but majorities of respondents reported isolating with COVID-19 symptoms (95.0%), covering their mouths when coughing and sneezing (82.4%), and always washing hands their regularly (79.0%). However, the majority (77.1%) of the participants indicated they had been to large gatherings within 14 days of the survey.66  One key predictor of adherence was reporting that health workers were a key source of information on the COVID-19 pandemic.

Whether or not individuals are vaccinated against COVID-19, PHSMs are and will continue to be essential factors in controlling the spread of COVID-19. Researchers expressed concern that increasing vaccination rates may boost complacency and lead to the further abandonment of PHSMs among vaccinated and unvaccinated individuals alike.

 

 

In Uganda, the COVID-19 pandemic and especially the enforcement of PHSMs such as movement restrictions during its early months had profound negative economic effects:

  • Economic growth slowed.
  • Movement restrictions led to business closures, increasing unemployment, and reducing household incomes.
  • Gender-based poverty increased.
  • Reduced household incomes led to food insecurity.

Surveys showed that these consequences disproportionately affected women, young people, refugees, and informal workers such as agricultural workers and small vendors.67,68,69

In March and April 2020, Uganda implemented interventions designed to mitigate these economic challenges.

Food distribution

To address food shortages caused by COVID-19 lockdowns and other measures, at the end of March 2020 Ugandan officials implemented a program for food distribution, funded by a supplementary budget and donations from partners in the private sector. Most of its beneficiaries were low-income urban households, the elderly and infirm, and nursing mothers. The program also gave priority to people in Kampala and the neighboring Wakiso district.

Each ration included salt, 6 kilograms of maize flour, and 3 kilograms of beans per person. Nursing mothers and the ill also received 2 kilograms of powdered milk and 2 kilograms of sugar.70,71

Reports indicate that there were flaws in this program: food was distributed slowly, its quality was sometimes poor, and many of Uganda’s most vulnerable households—including rural dwellers and refugees—did not receive any rations.64,72 In general, food distribution programs targeted the urban poor in Kampala, Wakiso, and Mukono. A countrywide survey conducted between May and June 2020 noted that only 13% of people received some food assistance: 24% of city dwellers reported getting food assistance, but only 7% of rural dwellers did.73,74

Receipt of government assistance according to survey conducted by the Partnership for Evidence-Based Response to COVID-19 (PERC) in September 2021

Partnership for Evidence-Based Response to COVID-19 (PERC), September 2021. The most recent survey sampled from Uganda consisted of 1,338 adults between September 20–30, 2021.

 

 

Social safety nets

Though COVID-19 led to the escalation of sexual and gender-based violence (SGBV) against children and women, few measures were in place to alleviate it. Formal safety nets such as toll-free lines and SGBV shelters were not readily available, and social distancing and other PHSMs meant that informal supports such as family, friends, and neighbors were also more difficult to reach or access.75  In a few communities, the NGO Save the Children supported litigation after the fact for children who had experienced some form of violence at home.76  

In some communities in Mayuge district, community leaders and volunteers used community radios and megaphones to encourage community members not to engage in sexual and gender-based violence. They used the same tools to communicate with community members who had been assaulted, telling them where they could report crimes and access SGBV services. Where they were used, these services were associated with reduced reports of SGBV.77

Psychosocial support

In some communities, Save the Children and other NGOs provided psychosocial support to clients through regular phone calls, home visits to families, and mini gamebooks and radio messages to reduce stress among children.78  

Obuntu bulamu is an ongoing research collaboration started in 2017 by Ghent University and public and private partners to improve participation, inclusion, and quality of life for children with disabilities in Central Uganda.79 This program implemented a peer-to-peer support intervention for those children—along with their nondisabled peers, parents, and teachers—in the Wakiso and Masaka districts in 2020.40

Uganda’s extensive experience managing previous epidemics gave it a strong surveillance infrastructure designed to detect local transmission of disease outbreaks early enough to slow their spread.80 This infrastructure included a national Integrated Disease Surveillance and Response (IDSR) framework that draws primarily from reports from community VHTs, staff at health facilities, and trained immigration staff at border points of entry (PoE).71,81,82 The country also had preexisting short message system (SMS) reporting platforms and response structures.

Some of these capacities were more localized. In the areas most affected by recent Ebola outbreaks, for example, some VHTs were trained to perform infection prevention and control, epidemic surveillance, and other aspects of outbreak response.

At the beginning of the COVID-19 pandemic, Ugandan officials could quickly employ these preexisting tools and facilities to monitor the intensity, geographic spread, and severity of disease and mobilize surge capacity, internal resources, and external emergency support.

The UVRI, which played an integral role in supporting COVID-19 surveillance across the board in Uganda, also increased its genetic sequencing efforts throughout the pandemic. This research helped track COVID-19 transmission in the country and build models to further improve data-driven decision making.83,84 ,85,86

 

 

Digital tools for COVID-19 surveillance

In 2017, Uganda’s MoH developed a National eHealth Strategy, which aimed to “harness and create an enabling environment for the development and utilization of sustainable, ethically sound and harmonized Information and Communications Technology at all levels to promote health and improve health services delivery in Uganda.”87  According to one analysis, Uganda’s health system used 91 digital health tools as of 2021. Of these, 35 were adapted or developed for COVID-19 response.73 Integration and interoperability of all systems with the National Electronic Health Information System was a persistent challenge.

Some of the tools that health authorities used to gather and share data for decision making during the COVID-19 pandemic are summarized in the table below.

 

Tool
Use Case Users

District Health Information Software 2 (DHIS2)

Reporting national health data through the National Health Management Information System (also an associated mobile app used extensively at points of entry) Ministry of Health
Health authorities at borders
Virtual Emergency Operations Center mailing platform (VEOCi) Compiling surveillance data from the various sources at the community level and submitting it to the national surveillance team
District surveillance focal persons
District health offices
Ministry of Health
Electronic Integrated Disease Surveillance and Response System (eIDSR)
Compiling surveillance data at health facilities and border points and submitting it to the national level Ministry of Health
Surveillance focal persons at health facilities and health authorities at border points
Open Data Kit for Surveillance
District-level reporting 
Ministry of Health
Surveillance focal persons at health facilities
Partners in the health sector
Electronic Results Dispatch System (eRDS)
Communicating test results
Health care workers
Eletronic Lab Investigation form (eLIF)
Sending test results via a direct data pipeline to the eRDS; it accompanies lab requests and facilitates case management
Health care workers
mTrac
Sending test results from facilities to the national level
Health care workers (testers responsible for reporting)
Smart Health App
Guiding VHTs through routine diagnostics, processes, and trainings
Village health teams (VHTs)
Go.Data
Collecting field data (primarily case data from the lab, hospitalizations, and contact tracing data)
Surveillance focal persons in the field
Ministry of Health

U-Report

Providing community engagement and messaging

Health care workers
Health facilities
Ministry of Health

 

 

Uganda had substantial laboratory infrastructure before the COVID-19 pandemic began (for testing and tracing for tuberculosis and HIV, for instance). Early in 2020, officials adapted some of this infrastructure to meet the new needs associated with the COVID-19 pandemic. The UVRI is a national reference and research center for the investigation of viral infections; its campus comprises five different laboratories, including the Vector Borne Disease Control Laboratory. Along with several other specialized laboratories, these were repurposed by the Central Public Health Laboratory for COVID-19 testing. Coordination among the various laboratories with different disciplinary strengths enabled collaboration with other countries and the standardization of testing procedures.

Lab worker Deborah Harriet sorts COVID-19 samples at the UVRI in Entebbe, Uganda, on January 21, 2022.
Lab worker Deborah Harriet sorts COVID-19 samples at the UVRI in Entebbe, Uganda, on January 21, 2022.
© GATES ARCHIVE. © 2022-2023 Exemplars in Global Health. All rights reserved.

However, in Uganda as elsewhere, testing supplies were limited, especially early in 2020.10 As a result, the country’s testing strategy was targeted and risk-based.88 Testing priority went to travelers from high-risk countries; some workers (such as truck drivers and traffic police officers) in border districts; symptomatic cases reported through community alerts; and contacts of confirmed cases, including those of health workers.3

At first, Uganda relied solely on polymerase chain reaction (PCR) tests, initially the only COVID-19 test the World Health Organization (WHO) recommended. Many health workers were familiar with these types of tests, which were already in use for HIV testing among infants, for instance.89  These PCR tests had to be sent to accredited laboratories, including the UVRI, the National Public Health Laboratory at Butabika, Tororo General Hospital, and Makerere University College of Health Sciences Laboratory at Mulago, for analysis.10

Health authorities soon adopted GeneXpert testing, which they were already using to diagnose tuberculosis and other diseases, for truck drivers at border points. This point-of-care testing delivered quicker results than PCR tests, sometimes in less than one hour.90,91

The country added rapid diagnostic tests (RDTs) to its official testing strategy in October 2020, and in December 2020 officials began to pilot RDTs to screen higher-risk people such as hospitalized patients, symptomatic health workers, and quarantined individuals.92,93 During this pilot phase, RDTs were used exclusively for screening; results were reported to the national lab database only after PCR tests confirmed them.

By June 2021, at the peak of Uganda’s second pandemic wave, RDT kits were widely distributed across the country, and official guidance recommended that they be used to screen all symptomatic people—symptomatic contacts of confirmed cases, symptomatic people seeking care at health facilities, and symptomatic people in congregate settings like prisons. During this period positive RDTs did not require PCR confirmation.94

 

 

Daily new COVID-19 tests per 1,000 people

Our World in Data, Uganda Ministry of Health

In August 2020, Ugandan authorities implemented a $65 fee for some test seekers, such as asymptomatic people and truck drivers at the border between Uganda and Kenya. Officials reduced that fee to $50 in October 2020.95 As of June 2021, health workers qualified for free testing (RDT or PCR) at public facilities, and free RDT testing was also provided at public health facilities for people seeking care.96  Others who wanted testing, including asymptomatic people, still had to pay for tests at private laboratories or government testing centers.97

Uganda’s limited, targeted testing strategy kept many infections undetected in the early part of the pandemic. Sample collection was allowed only at specific accredited sites, which forced some eligible people to travel long distances for a free test. Meanwhile, asymptomatic people—who were not eligible for free tests—may not have received them. In that case, they could not have known that they had contracted COVID-19, leading to underreporting and viral spread.

Even when tests were available, the stigma associated with testing positive for COVID-19 (one report even quoted health officials speaking of “hunting down” suspected patients98) pushed some people to avoid them. This limited opportunities for early detection, treatment, and mitigation of viral spread.99 Informants reported that there were times when the supply of free tests outstripped demand.

Because of these gaps in Uganda’s testing data, additional information—such as excess mortality and serological surveillance data—may help establish a clearer picture of the disease burden in Uganda. Researchers have been conducting seroprevalence studies for human coronaviruses at hospital sites in Uganda since before the COVID-19 pandemic began,100 continuing through 2020 and 2021.101 Serological findings suggested a higher exposure to COVID-19 in the general population than testing data reflects.100

WHO statistics on excess mortality showed more than 20,500 excess deaths in Uganda from the beginning of the COVID-19 pandemic through the end of 2021102 —far more than the 3,291 COVID-19 deaths officials registered.103 This gap, too, may have reflected the country’s limited and targeted testing strategy. However, Uganda’s MoH disputed these figures.94

As a result of its experience with previous epidemics, Uganda already had a contact tracing infrastructure and trained workforce in place before the COVID-19 pandemic began.

For instance, during the Ebola outbreak in 2018–2019, the National Task Force coordinated preparedness efforts and field response, including epidemiological surveillance. In the highest-risk districts, mostly along the country’s western border and around Kampala, rapid response teams provided disease surveillance training to health workers, VHTs, and others, including police and security forces. Volunteer screeners worked in health facilities, border PoE, refugee reception centers, and communities.104 This work aimed to limit the importation and spread of Ebola in Uganda. Only four cases were reported—all of which officials believe were imported from a neighboring country—and no in-country infections or transmission.105

Applying these tools, experience, and trained personnel, Uganda performed intensive COVID-19 contact tracing from March to September 2020. During this period, contact tracing occurred in a top-down fashion: central teams deployed to health regions worked with regional surveillance, case investigation, and case management teams. Contact tracers often used WHO’s Go.Data tool to collect patient data using mobile phones.106

As COVID-19 case counts increased after the end of the national lockdown in May 2020, overwhelming the capacity of this centralized contact tracing strategy, in some districts local community health workers, volunteers, and students began to aid epidemiologists’ contact tracing efforts.24 (Most were unpaid, but one report notes that some received stipends, training, T-shirts, and other incentives.)99 This decentralized approach aimed to build community engagement and capacity and improve the efficiency of contact tracing in the COVID-19 context.

However, even as decentralized efforts expanded, challenges persisted. For instance, despite the many volunteers recruited to support the task, limited testing made it difficult to confirm cases and link them to a source of infection. Communication was delayed. Cases and contacts were sometimes uncooperative, perhaps due to the stigma associated with COVID-19 infection. Logistics were also a challenge: as one analysis notes, in some cases “contacts were not tested due to inadequate laboratory supplies, fewer contacts were followed up due to limited transport and some contacts were forced to use public transport to health facilities for sample collection which risks increased transmission of the virus.”24

Prior to the COVID-19 pandemic, Uganda’s rates of immunization coverage were generally high: in 2020, the national rates of immunization against DPT3 and measles were 94% and 87%, respectively.107 These immunization programs were mostly donor-funded.

A robust cold chain infrastructure is essential for storage and delivery of essential vaccines, including vaccines against COVID-19. In Uganda, with help from partners such as Gavi, the Vaccine Alliance and UNICEF, the National Expanded Program on Immunization had already begun to establish a functional cold chain system powered by electricity, solar, and LPG gas before the COVID-19 pandemic began.108  In 2020, Uganda had 128 established district vaccine stores and approximately 3,213 health facilities equipped with cold chain equipment.109

Nurse Rhode Guloba administers a COVID-19 vaccine at the Makerere University Hospital in Kampala, Uganda, on January 19, 2022.
Nurse Rhode Guloba administers a COVID-19 vaccine at the Makerere University Hospital in Kampala, Uganda, on January 19, 2022.
© GATES ARCHIVE. © 2022-2023 Exemplars in Global Health. All rights reserved.

In December 2020, Uganda issued its first deployment plan for COVID-19 vaccines. This document outlined the country’s strategies to vaccinate vulnerable populations, ensure the availability of adequate and viable vaccines, train health workers to provide and manage the vaccination process, generate demand, and monitor the implementation of the vaccination program.110

Starting in March 2021, when Uganda received its first batch of COVID-19 vaccines from COVAX, the country’s vaccination campaign targeted high-risk groups: health workers, security personnel and other frontline workers, people older than 50, and people with certain comorbidities.111However, the early vaccination campaign lagged. Reports indicate that initial efforts focused on just a few vaccination sites, mostly in cities; eligible people in rural or hard-to-reach locations had to travel long distances to find doses. Limited vaccine sites also meant long lines and, sometimes, supply shortages.112

Even though increasing the rate of vaccine coverage would enable the reopening of the economy and reverse some of the negative impacts of the PHSMs that Uganda had implemented to control COVID-19 spread, the country’s vaccination campaign was met with some hesitancy. One study found that majorities of participants lacked information about the COVID-19 vaccine and its availability in their districts. Some believed that officials should be immunized first. About 15% attributed their hesitancy to misconceptions that were relatively common worldwide, such as that the vaccine could cause infertility or infect recipients with COVID-19, or that COVID-19 was not a serious illness.112

 

 

Initially, the cause of low vaccination rates in Uganda was not vaccine hesitancy but the lack of vaccine availability.113 Starting in August 2021, when the country received more doses of vaccines, all Ugandans 18 years and older were eligible for vaccination. Even so, at that time, vaccines were still available mostly through designated health facilities where many eligible people could not access them. Later, authorities worked with local governments and NGOs to increase access via outreach programs and mobile vaccine sites.107,114,115

By the end of December 2021, just 3% of Ugandans had received a complete dose of the COVID-19 vaccine, and 15% were partially vaccinated.95

Daily COVID-19 vaccine doses administered per 100 people in Uganda, Africa, and globally

Our World in Data
Case study: COVID-19 vaccine uptake in Uganda

A study conducted in November 2021 by researchers at the Makerere University School of Public Health and the Massachusetts Institute of Technology examined the factors associated with COVID-19 vaccine uptake and intention to vaccinate in Uganda.116

The COVID-19 vaccination campaign at the Makerere University Hospital in Kampala, Uganda, on January 19, 2022.
The COVID-19 vaccination campaign at the Makerere University Hospital in Kampala, Uganda, on January 19, 2022.
© GATES ARCHIVE. © 2022-2023 Exemplars in Global Health. All rights reserved.

Several key lessons arose from the study.

1.Health workers can be a key resource.

Previous studies reported that health workers’ advice on vaccination was highly trusted.117,118 Consequently, providing health workers with accurate and sufficient public-health information to share with their clients and communities may boost vaccine confidence and uptake.

At first, vaccine uptake among health workers themselves was reportedly low—even though they were a priority group from the start of the Ugandan vaccination campaigns. An in-depth study of health workers reported lack of trust in the vaccine, fear of side effects, not feeling at risk, lack of sufficient information about vaccines, health systems challenges, and religious beliefs as barriers to COVID-19 vaccination (see figure below).120

Researchers argue that when health workers receive a vaccine, they are more likely to recommend that their patients do the same.121 Health systems should address vaccine hesitancy among health workers if they are to be maximally effective champions for COVID-19 vaccination.

Reasons stated for nonvaccination against COVID-19 in Uganda in November 2021

Makerere University School of Public Health

2. Health systems should disseminate accurate information as widely as possible.

In Uganda, education status predicted vaccination status. This is not surprising, as it reflects the findings of previous research on vaccine acceptability.122,123  Further efforts are required to ensure dissemination of accurate information to people with lower levels of education, including via public health messaging in local languages. (See figure below.)

Reasons stated for vaccination against COVID-19 in Uganda

Makerere University School of Public Health

3. Trust in health systems is a key determinant of vaccine uptake.

Half of the study participants reported high levels of trust in the Uganda MoH’s handling of the COVID-19 pandemic, and a positive perception of their competence was associated with vaccination uptake. More generally, researchers have highlighted trust in government as a key determinant of uptake of public health interventions: studies from Nigeria,124 the Democratic Republic of the Congo,125 Brazil,126 Thailand,127 and China128 analyzed links between trust and compliance with PHSMs, and mostly found a positive association between trust and vaccination. In Uganda, study participants were more willing to adopt health officials’ recommendations to vaccinate than traditional leaders’. The MoH should intensify its vaccination education campaigns and make efforts to strengthen public trust via risk communication and community engagement. It should also work to increase access to COVID-19 vaccines across Uganda.

4. Health systems should make efforts to bridge the intention gap.

The study found that the intention to vaccinate among unvaccinated people was much higher (91.0%) than it had been in a March 2021 survey (57.8%) conducted by the same research team.57 The high mortality that Uganda experienced during the delta wave129 could have contributed to this change. Respondents also reported a concern that at some point unvaccinated Ugandans would be denied health and social services, which could also have boosted their intention to be vaccinated.

A November 2021 survey of 23,000 people from 19 African Union member states including Uganda found that 78% of respondents had either been vaccinated or were likely to get vaccinated (note that as of December 2022, less than 30% of Africans are fully vaccinated against COVID-19).130  The survey concluded that low vaccine uptake was due more to unpredictable supply of vaccines and logistical hurdles than reluctance or refusal to get vaccinated.127 Evidence suggests that strategies that bring vaccines closer to communities (such as extending vaccines to more health facilities, establishing mobile vaccination or service points, and conducting regular outreach) are likely to mitigate time- and transport-related barriers and increase vaccine uptake.131 ,132

In general, the study found that efforts are needed to increase access to vaccines, utilize health workers as a key information resource, and strengthen trust in the MoH. All of these should positively affect vaccine uptake as well as adherence to PHSMs.

The COVID-19 vaccination campaign at the Makerere University Hospital in Kampala, Uganda, on January 19, 2022.
The COVID-19 vaccination campaign at the Makerere University Hospital in Kampala, Uganda, on January 19, 2022.
© GATES ARCHIVE. © 2022-2023 Exemplars in Global Health. All rights reserved.

 

 

Health system-level response measures

In the early months of the pandemic, Uganda’s health system-level response measures divided into two main categories: direct responses to COVID-19, and interventions for the maintenance of EHS.

In many countries around the world, the COVID-19 pandemic and efforts to mitigate it caused supply- and demand-side barriers to EHS delivery. These barriers included provider and patient fear of infection in health facilities; inability to travel due to lockdowns; budgetary shortfalls; and delays and stockouts of essential health commodities such as PPE, reagents, some vaccines (such as for HIV), and critical diagnostic tools (such as GeneXpert cartridges).

In Uganda, movement restrictions and physical distancing guidelines were significant obstacles to EHS delivery, especially in the early months of the pandemic (see figure below). For example, lockdowns—and the deployment of police and other security personnel to enforce them—kept many health care providers from their workplaces. Media reports that police prevented patients from seeking routine care, contrary to lockdown guidelines, might have affected public demand for that care.133

Trends in Ugandan households missing needed health care during the pandemic

: Partnership for Evidence-Based Response to COVID-19 (PERC) in partnership with Ipsos. The most recent survey sampled from Uganda consisted of 1,338 adults between September 20 – 30, 2021.

Among Ugandan households that needed medical care in the first six months of the pandemic, more than half delayed or skipped it. The most frequently cited reason for skipping health care visits was lockdown-related mobility restrictions (see figure below).131

Reason for delayed, skipped, or incomplete health care visits in Uganda

Partnership for Evidence-Based Response to COVID-19 (PERC) in partnership with Ipsos as of September 2021. The most recent survey sampled from Uganda consisted of 1,338 adults between September 20–30, 2021.

Indicator data appears to show that the movement restrictions Uganda implemented in April 2020 undermined the delivery of EHS such as immunization for diphtheria, tetanus, and pertussis and outpatient treatments for noncommunicable diseases such as diabetes mellitus and hypertension. This appears to have been especially true in urban areas in the central region of Kampala and Wakiso.

After movement restrictions were lifted in May 2020, indicator data appears to show that some barriers to key services, such as in-facility births and outpatient health visits, persisted. Other factors, such as patient fear of contracting COVID-19 at health care facilities may have affected these trends as well.

Interrupted time series of in-facility births in Uganda

Routine Health Systems Data from Makerere University School of Public Health

Interrupted time series of outpatient health visits

Routine Health Systems Data from Makerere University School of Public Health

Maintaining the delivery of EHS during and after the 2020 lockdowns was a key pillar of Uganda’s early COVID-19 response. To fund it, officials deployed resources from international partners, NGOs, and other pillars of the pandemic response. UNICEF, the Netherlands Embassy, and the Global Fund to Fight AIDS, Tuberculosis and Malaria contributed millions of dollars to support the emergency response and maintenance of EHS.

In Uganda, the COVID-19 pandemic compelled the implementation of service-delivery adaptations in nearly every sector of public life—and Uganda’s telecom service providers earned record revenue in the second half of 2020, perhaps as a result.134,135 For example, several companies introduced online ordering and door-to-door delivery of essential goods such as food and medicine, which had not previously been common even in urban areas such as Kampala.136 Some formal-sector workplaces adopted virtual platforms for meetings, trainings, and telework during lockdowns.137,138   However, as in other countries, this shift was concentrated among skilled workers in professional jobs, a small minority of Uganda’s workforce as a whole.139

The pandemic likewise pushed Ugandan health care providers to speed their adoption of digital technologies enabling the remote delivery of clinical and nonclinical health services—including virtual health worker training, continuing medical education, and administrative meetings as well as long-distance patient care. Stakeholders such as the medical concierge group, the Infectious Diseases Institute, and Baylor Uganda adopted telehealth services in areas including HIV/AIDS; tuberculosis; maternal, newborn, and child health; and sexual and reproductive health services.140

These telemedicine applications enabled activities from teleconsultations with care providers (including telepsychiatry and telepharmacy services) to the dissemination of health information and appointment reminders via mobile phones, and they helped maintain access to care during the early months of the COVID-19 pandemic in Uganda.135

“Of course, technology for meetings was more embraced as there was a ban on physical meetings. We also embraced technology for follow-up of cases for instance in contact tracing. So, we saw a lot of innovations, which was a positive thing.”

- Policymaker, Ministry of Health

However, most telemedicine providers were located in Kampala, which made it difficult for far-flung patients who needed further in-patient care. Other challenges included lack of electronic medical records, limited availability in languages other than English, the prohibitively high cost of Internet connectivity, and some telehealth providers’ limited technical capacity. 135

Community health workers Ronald Tenywa (c), Muwangala Herbert (r) and David Kiirya (l) during a polio vaccination campaigns in Buyende, Uganda on January 17, 2022.
Community health workers Ronald Tenywa (c), Muwangala Herbert (r) and David Kiirya (l) during a polio vaccination campaigns in Buyende, Uganda on January 17, 2022.
© GATES ARCHIVE. © 2022-2023 Exemplars in Global Health. All rights reserved.
Case study: Maintaining HIV treatment during the COVID-19 pandemic in Uganda

Between June and September 2020, researchers conducted a qualitative study in eight districts in eastern and western Uganda to investigate perceptions related to community-based strategies for dispensing antiretrovirals (ART) to HIV clients during the COVID-19 pandemic. Respondents were providers and recipients of HIV care.141

The study found that access to care was maintained by providing six months of ART refills, involving patient peer leaders in drug distribution, using community drug distribution points instead of pharmacies in health care facilities, and using COVID-19 response resources to distribute medicines. However, challenges remained. For instance, due to the stigma associated with HIV, some clients provided incorrect home addresses to care providers to prevent unintentional disclosure of their HIV status to neighbors and other community members. Also, community drug-distribution points could reduce available supplies at health facilities.141

Another study among 100 HIV clients on ART found that although the pandemic and the movement restrictions instituted to control the spread of COVID-19 negatively affected access to care, some respondents noted that the stay-at-home orders facilitated adherence to treatment because they did not have to travel to work. 142

 

 

During the early months of the pandemic, Ugandan health facilities stretched the capacity of their workforces by taking advantage of the ability of nonmedical staff to do essential jobs such as temperature screening at health facilities. MoH guidelines recommended shifting tasks such as temperature and symptom screening and some EHS to VHTs wherever possible.143  

Task shifting among health workers was not a new practice in Uganda. In fact, to address the country’s persistent shortage of higher-skilled health workers, less-skilled workers have been delivering care to patients with HIV, tuberculosis, and malaria as well as EHS (such as maternal, newborn, and child health) at many levels of the system for generations.144,145

During the COVID-19 pandemic, many health workers were redistributed to boost the maintenance of EHS and to provide services associated with COVID-19 prevention, surveillance, and care.10 In some districts, staff were recruited and redeployed to maintain EHS, while others were assigned to provide care at COVID-19 facilities. For example, health workers—including epidemiologists, doctors, anesthetists, nurses, laboratory technologists, psychiatric clinical officers, ambulance assistants, and drivers—were deployed on six-month contracts to COVID-19 treatment centers and to support districts and PoE in surveillance.

When possible, officials provided VHTs and other staff delivering in-person services with protective gear.146 This practice also helped ensure the maintenance of critical community-based services such as indoor residual spraying (IRS) for malaria and mosquito control and integrated community case management of childhood illnesses.141

 

 

In addition to health services, CHWs also supported contact tracing and community education about COVID-19. However, movement restrictions limited these services to community members who lived near the homes of CHWs.147 Finally, some health facilities provided safe accommodations, such as in hostels, for health workers during lockdowns. However, this practice was infrequent and not sustainable over the long term.148

Where it was not possible to enable patients and providers to avoid health facilities via telehealth and other means, Ugandan authorities adapted preexisting facilities to facilitate the in-person delivery of both COVID-19 treatment and EHS. These separate facilities aimed to minimize contact between COVID-19 patients and patients seeking other kinds of health care and enabled service delivery at other levels of the health system.

As of July 2021, Uganda had 3,793 beds in health facilities for COVID-19 patients. 218 of these were intensive-care beds: 27 at the Mulago National Referral Hospital and the rest at regional referral hospitals (which had an average of 10 ICU beds each), military hospitals, and accredited private facilities.149  In September 2020, the MoH converted parts of the Mandela (Namboole) National Stadium on the outskirts of Kampala into a field hospital planned to hold more than 1,000 people at a time. (Authorities expected it would treat mostly asymptomatic and mild cases in isolation.)150  The stadium hospital closed as the surge waned, but reopened In July 2021 when the second wave increased case counts dramatically.151

To ensure rapid response to emergency COVID-19 cases, the MoH deployed a fleet of 50 ambulances for the Kampala metropolitan area, along the major highways and at selected regional sites from the end of December 2020 to the end of January 2021.152

Officials also designated clinics for EHS delivery, such as young-child clinics for maternal and child health.

Service delivery was adapted in other ways as well. For instance, in the West Nile region, the Association of Volunteers in International Service Foundation and UNICEF secured official clearance for boda-boda motorcycle drivers to transport mothers and young children to health facilities for medical attention even when movement restrictions prohibited boda-bodas from carrying passengers. The NGOs trained the drivers on the MoH guidelines for COVID-19 prevention and control and gave them hand sanitizer and face masks.153  Localized interventions like this one helped ensure the continuity of EHS delivery for mothers, newborns, and children.154

To prevent stockouts of essential supplies such as PPE and diagnostic tools, health officials used preexisting national distribution mechanisms, procurement plans, and digital platforms such as eLIMS to enable the transfer of goods from one health facility to another.155   By July 2021, with the help of partners such as USAID, Uganda had established a digital system for ordering and distributing key commodities (such as PPE, medicines, and oxygen supplies) to district health facilities.155 The MoH’s Pharmacy Division reviewed family-planning procurement plans and asked the National Medical Stores to supply facilities accordingly.

Partnerships with organizations like the Global Fund, Africa Centres for Disease Control, WHO, and many others helped Uganda ensure continuous delivery of EHS156 and boost local manufacturing of key goods such as PPE, reducing its overreliance on imports for health and related commodities.157,158

Vaccinator Jonan Mweteise (r) carries out COVID-19 vaccinations at the Makerere University Hospital in Kampala, Uganda, on January 19, 2022.
Vaccinator Jonan Mweteise (r) carries out COVID-19 vaccinations at the Makerere University Hospital in Kampala, Uganda, on January 19, 2022.
© GATES ARCHIVE. © 2022-2023 Exemplars in Global Health. All rights reserved.

Patient-level measures

Starting in April 2020, Uganda’s government required a minimum 14-day isolation for confirmed cases of COVID-19. A 14-day quarantine was required for close contacts of confirmed cases and for most international travelers entering the country.159 Both isolated and quarantined individuals were to be tested at least twice, on the first and last day of isolation, and had to obtain a certificate with proof of a negative test before they could leave. 159 However, as community spread increased and the cost of testing grew accordingly, Uganda modified this policy. Starting in October 2020, follow-up testing at the end of isolation or quarantine was no longer recommended for asymptomatic people.160  

Isolation

Initially, health officials in Uganda isolated all confirmed COVID-19 patients at designated health care facilities.159 As case counts increased, secondary regional isolation centers (including the one at the Mandela National Stadium) were used to manage nonsevere but high-risk patients. Subsequently, officials implemented home-based isolation nationwide for asymptomatic people who tested positive for COVID-19 cases and those with mild symptoms and no known risk or comorbidity.

Medical teams under the guidance of district task forces contacted isolated patients daily to monitor their symptoms. Patients could also contact the medical surveillance team using a national toll-free hotline.159 Where VHTs were active, they monitored patients through phone calls and submitted daily reports to local health facilities.144

Quarantine

At first, officials asked all travelers who tested negative to quarantine at home,161 but weak enforcement and low levels of compliance soon pushed officials to implement institutional quarantine. In April 2020, they established 17 quarantine centers around Kampala and Entebbe and additional centers in 21 districts. The MoH’s surveillance team organized the collection of a sample for testing, and if it was positive the patient would be moved to a case management team.158

Medical teams were supposed to monitor quarantined patients daily, but key informants report that this was rarely done. According to an online survey conducted by MoH in April 2020, health workers checked just 59% of those in institutional quarantine every day—and of those, only 19.9% in self-quarantine reported daily checks.162 Because quarantine could not be fully enforced, individuals were often exposed to others who had recently tested positive, prolonging the observation period for contacts.

Uganda’s quarantine centers were typically established in hotels, and quarantined travelers had to pay the bills themselves. Other challenges included insufficient space and overcrowding in quarantine facilities, risk of repeated exposure that delayed discharge, limited PPE, and suboptimal health monitoring.163,164   The institutional quarantine program was also marred by neglect, dissatisfaction, and mismanagement (which was frequently reported in the media).165

By September 2020, institutional quarantine was no longer required for returning travelers with negative PCR tests at PoE. Instead, they were advised to limit contact with other people for two weeks. Testing was also no longer required for asymptomatic people at the end of their quarantine.

Institutional isolation was reintroduced at the peak of the second wave in May 2021 for incoming travelers who tested positive for COVID-19 at PoE.166 However, the implementation was short-lived and not strictly enforced.

In June 2021, Uganda’s National Drug Authority granted marketing approval of an herbal medicine, Covidex, to treat COVID-19 symptoms.167 Most Ugandans were not yet eligible for the vaccine at that time, and reports indicated that the use of this and other herbal medicines to prevent and treat COVID-19, even among hospitalized patients, was widespread.168,169

Note that treatment and care for COVID-19 was not a focus of this research.

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Challenges