Synthesis of Research Evidence
ACCEPTABILITY
Care-seeking at facilities increased, but remained <50% or lower
FEASIBILITY
Scale up to having some IMCI facilities in all regions by within one year
Full coverage was not achieved as planned
Implementation strategies include:
Pilot testing and adaptation
Adaptation to reflect updated national treatment guidelines
Donor and implementing partner support and coordination
Pre-service training and reduction in training duration
Use of country experts and professional organizations
FIDELITY
Only 28% of facilities assessed in 2014 ESPA+ had at least one staff member who received in-service training (although may under estimate as preservice training had expanded)
<50% of children by 2016 seeking care for the 3 main areas (Fever, diarrhea, ARI) from facilities and varying rates of correct diagnosis and treatment
EFFECTIVENESS/REACH
While improved, less than 50% of children under 5 with diarrhea, ARI, and fever received care at facilities (see Figure 13)
Decrease in deaths attributed to lower respiratory infections (14.6% to 13.1%) and malaria (2.4% to 0.4%) from 2000 to 2015, though no improvement in diarrhea-related mortality (12.7% to 15%)1
IHME DECOMPOSITION RESULTS.1
<1% of the reduction in under-five mortality attributed to oral antibiotics, ORS, zinc treatment, and ACTs
Synthesis of Research Evidence
ACCEPTABILITY
Lower care seeking (9%) from HEWs compared to higher-level public facilities (16%) in 20132
FEASIBILITY
By 2014,
-- Nearly 30,000 HEWs in 8 regions participated in iCCM
-- iCCM implemented in 86% of districts nationally3
High availability of curative child services at health posts (96%) per 2014 ESPA+
FIDELITY
A 2012 study found that HEWs in areas implementing iCCM correctly classified 53% of children for all major iCCM illnesses. Similar gaps in quality were reported by the 2014 SPA.
EFFECTIVENESS/REACH
Care-seeking behavior impacts utilization and coverage of iCCM services
Synthesis of Research Evidence
ACCEPTABILITY
Ongoing community perception of diarrhea as disease not requiring care at a health facility
FEASIBILITY
Low availability of ORS and zinc at health facilities, although some increase by the end of the study period and high rates of ORS
High availability of FB-IMCI and iCCM services at facility levels
Variable rates of recent provider training (possibly underestimated due to pre-service training)
Challenges with maintaining stocks
FIDELITY
Low rates of providers receiving in-service training on diarrhea diagnosis and treatment in 2014 – 43% in health posts and 7% in all other facility types
Low provider adherence to national guidelines and preference to prescribe antibiotics in facilities, varying use of zinc
EFFECTIVENESS/REACH
2014 – ORS given to only 29% of children with diarrhea without dehydration and 66% of those with dehydration treated at health facilities excluding health posts and zinc given to only 16% and 8%, respectively
Higher coverage of ORS at health posts (100%), but no administration of zinc
Per key informant, growing proportion of diarrhea cases treated in private facilities but tendency to prescribe antibiotics rather than ORS and zinc at these facilities, requiring future efforts to address treatment in the private sector
Remaining inequities in coverage – per KI, possibly due to higher health literacy and access in urban areas, as well as cultural practices in rural areas:
“We come to the cultural or traditional practices, the more rural I would say people may stick to the tradition and avoiding that meal or this meal and giving that tradition-based intervention…”
Synthesis of Research Evidence
ACCEPTABILITY
No evidence of rejection by the community
FEASIBILITY
Available in all regions as planned and stocked
Outreach activities conducted
Sustainment or increase in rates with UNICEF/WHO estimated coverage increased to 80% in 2016 and 20174
Integrated into national EPI program
FIDELITY
EFFECTIVENESS/REACH
UNICEF/WHO coverage estimates of infants receiving the 2nd dose of rotavirus vaccine:
- 2014 – 56%
- 2015 – 79%4
The 2016 DHS reported the following. This shows some remaining inequities in coverage
- Overall coverage of 64% for 1 dose and 56% for 2 doses of rotavirus vaccine
- Regional variation in coverage – from 23% in Afar to 92% in Addis Ababa for 2 doses
- Higher coverage in urban areas compared to rural ones (79% and 53%, respectively, for 2 doses)
18% reduction in proportion of diarrhea hospitalizations due to rotavirus in children under 1 year, decline in seasonal peaks of disease5
IHME DECOMPOSITION RESULTS
21.4% of the reduction in under-five mortality attributed to vaccines including rotavirus, PCV, Hib, Measles, DTP3, and Meningitis.1
Synthesis of Research Evidence
ACCEPTABILITY
High levels (nearly 100%) of general acceptability of vaccines in the community, according to interviewees in a 2015 study
FEASIBILITY
PCV successfully introduced and no stockouts noted
Integrated into national EPI program and strengthening of surveillance planned
FIDELITY
EFFECTIVENESS/REACH
Increases in coverage for vaccination in all geographic districts and both urban and rural areas but remained below targets
Challenges with achieving coverage goals
WHO/UNICEF estimates of coverage of PCV3 increasing from 12% in 2011 to 76% in 20156
The 2016 DHS reported:
- PCV3 coverage varied by region, ranging from 18% in Afar to 91% in Addis Ababa
- Urban areas (73%) had higher PCV3 coverage than rural ones (46%)
- Variable coverage by wealth quintile, ranging from 36% in the lowest quintile to 71% in the highest
Synthesis of Research Evidence
ACCEPTABILITY
Delayed introduction following global shortage
Introduction in all regions achieving coverage shown in Effectiveness and Coverage (Reach)
No evidence of stockouts seen and ongoing commitment to continued vaccination
FIDELITY
2012 cluster survey indicated 26% dropout between Penta 1 and Penta 37
EFFECTIVENESS/REACH
High Penta 3 coverage in 2016 per administrative estimates (96%), though lower coverage estimated by WHO/UNICEF (73%) and DHS (53%) with significant gaps
Variability of coverage at regional level – from 20% in Afar to 96% in Addis Ababa per 2016 DHS
Lower coverage in rural and lower wealth populations in 2016
Synthesis of Research Evidence
ACCEPTABILITY
Remaining belief in communities that measles is not severe per key informant
Required separate visit at 9 months of age
FEASIBILITY
Measles vaccines given both as routine and through catch-up as well as targeted to meet needs of refugees
Large numbers vaccinated
Measles vaccination is an integral part of the national U5M reduction strategy and in the HMIS and EPI schedule
FIDELITY
EFFECTIVENESS/REACH
2015 coverage: 65% per WHO/UNICEF estimates, 92% per FMOH
See equity
Increased in number of measles cases over study period, believed to be due partly to increased sensitivity of surveillance system
Decrease in U5 proportion of measles cases from 56% in 2008 to 30% in 20148
Acceptability issues limit coverage
Per 2016 DHS, gaps in coverage between wealth quintiles (43% in lowest quintile to 74% in highest)
Large regional variation in coverage per 2016 DHS – from 30% in Afar to 93% in Addis Ababa
Synthesis of Research Evidence
ACCEPTABILITY
High vaccine acceptance per FMOH
FEASIBILITY
All 3 phases completed as planned as a single dose campaign
FIDELITY
EFFECTIVENESS/REACH
High coverage in target areas per FMOH post-campaign coverage surveys:9
- Phase 1: 98.4%
- Phase 2: 97.6%
- Phase 3: 93%
High coverage across the country, with limited geographic variation (from 88% in parts of Afar to 97% in parts of Tigray)
Synthesis of Research Evidence
ACCEPTABILITY
Per National Malaria Indicator Surveys (2007, 2015) only 2/3 of nets were used the night before the survey
FEASIBILITY
Widespread distribution was feasible
Delivery achieved through using multiple approaches including outreach to ensure coverage
Reliance on external funding and procurement of nets limits sustainability
FIDELITY
Targeting for higher risk areas
EFFECTIVENESS/REACH
Per MIS: Household ownership of ITNs reached 66% in areas <2000m in 2007 and remained steady (64%) through 2015
MIS: In 2015, almost half (49%) of the population had access to an LLIN. LLIN access varied by region – from 24% in Harari to 59% in Tigray.
MIS: decline in all-age parasitemia (by RDT) from 4.5% in 2011 to 1.2% in 2015, under-5 parasitemia of 1.4% in 2015
Access to an LLIN in the household in 2015 varied by region, from 24% in Harari to 59% in Tigray
Access to an LLIN in 2015 varied moderately by wealth quintile:
Lowest – 35%
Highest – 50%
Synthesis of Research Evidence
ACCEPTABILITY
No refusal data found
FEASIBILITY
IRS was able to be implemented (although see reach)
HEWs able to support expansion of community-based spraying to targeted communities
FIDELITY
In 2013, compliance with standard spraying procedures was 81% in districts using community-based IRS and 92% in those using district-based IRS10
2013 spray quality assessment in Oromia found mortality of mosquitoes exposed to sprayed walls to be 99.5% in district-based IRS districts and 99.9% in community-based IRS districts11
EFFECTIVENESS/REACH
2001-2005 target for IRS (60%) not met (30%) due to lack of funds
Coverage in targeted regions was higher – 92% of targeted structures were sprayed in 2015/16
significant regional variability
Synthesis of Research Evidence
ACCEPTABILITY
Increased uptake of ART and adherence reported by 2009 MSG program evaluation suggested high acceptability
High acceptance of provider-initiated testing – 92% of counseled mothers receiving ANC at facilities providing PMTCT services accepted testing in 2010
FEASIBILITY
PMTCT implemented although challenges with reach
ART coverage remained <90% and even saw drop in ART coverage for pregnant women to 62% in 2015-201612
Significant reliance on donor funding
FIDELITY
52% of facilities assessed in 2014 ESPA+ reported having at least one staff member recently trained on PMTCT
The HIV/AIDS Strategic Plan for 2015-2020 identified several existing gaps in the PMTCT program, including inadequate integration of option B+ into the MNCH platform, weak monitoring and evaluation system for PMTCT, poor access to and utilization of facilities for early infant diagnosis, and low skilled birth attendance coverage
EFFECTIVENESS/REACH
2016 DHS reported 34% of pregnant women were tested for HIV during ANC or labor and received results
70% ARV coverage for PMTCT in 2014
New pediatric cases averted due to PMTCT
WHO estimated that the final MTCT rate (including the breastfeeding period) in Ethiopia was 16% in 201613
Regional variation in testing for HIV during ANC or labor in 2016 DHS – from 6% in Somali to 78% in Addis Ababa
Regional differences in MTCT, from 4.2% in SNNPR to 15.7% in Dire Dawa14
IHME DECOMPOSITION RESULTS1
<1% pf the reduction in under-five mortality attributed to PMTCT and ART
Synthesis of Research Evidence
ACCEPTABILITY
Per key informant, coverage may be impacted due to stigma around HIV and household prioritization of care for adults rather than children.
FEASIBILITY
Expansion of HIV testing and ART facilities including infants and children
FIDELITY
Below-target coverage of testing (timing and testing) of HIV-exposed infants
EFFECTIVENESS/REACH
2012 survey of five facilities in Amhara found that only 41% of HIV-exposed infants had blood taken for testing at or prior to 6 weeks of age.
31% estimated coverage of early infant diagnosis in 2015
Improved coverage of children under 15 receiving ART – 1% in 2005/6 to 25% in 2014/15, but still major gaps
Substantial decrease in related mortality in children between 2002 and 2016
Synthesis of Research Evidence
ACCEPTABILITY
Data not found
FEASIBILITY
National scale-up of SAM management through national scale of FB-IMCI and iCCM
FIDELITY
2011 study found that a large portion of children admitted to health post treatment programs with SAM were discharged while still classified as having SA M15
EFFECTIVENESS/REACH
High availability of SAM diagnosis and treatment at public health facilities (84%) in 2016
SAM diagnosis and treatment widely available at the community level – offered in 82% of health posts
Variable recovery rates reported
IHME DECOMPOSITION RESULTS
32% of the reduction in under-five mortality attributed to reductions in child growth failure and reductions in vitamin A and zinc deficiency.1
Synthesis of Research Evidence
ACCEPTABILITY
Data not found
FEASIBILITY
Scale-up of Enhanced Outreach Strategy
High coverage across regions as seen below
FIDELITY
EFFECTIVENESS/REACH
94% national coverage in 2008, ranging from 82% in Dire Dawa to 99% in Tigray
DHS: coverage of 53% in 2011 and 45% in 2016
Coverage varying by region in 2016 DHS (from 35% in Afar to 74% in Tigray)
Synthesis of Research Evidence
ACCEPTABILITY
Although data on acceptability was not found, the uptake of HEW-delivered ANC was limited despite increased access to these services at the community level, through inclusion of ANC in the scope of HEWs
FEASIBILITY
87% of facilities assessed in 2014 ESPA+ reported providing ANC services
FIDELITY
In 2014, 54% of facilities providing ANC reported having at least one staff member who received in-service training for ANC care
Low availability of guidelines at facilities (2014 SPA)
EFFECTIVENESS/REACH
Per DHS, utilization of any ANC visits increased from 27% in 2000 to 62% in 2016.
Low remaining utilization rates
Persistent low ANC4+ rates with only 32% reach by 2016
Improvement in ANC1+ rate with 62% reach by 2016
According the 2000 DHS and 2016 DHS, women in rural areas were less likely to receive ANC from skilled provider (22% and 58%) in comparison to those in urban areas (68% and 90%) respectively
Regional variation from 51% in Afar to 97% in Addis Ababa (DHS 2016)
ANC by a skilled provider remained at 76% in urban areas versus 26% in rural areas.
IHME DECOMPOSITION RESULTS
2% of the reduction in U5M attributed to increased use of skilled birth attendants. An additional 2% of the reduction in U5M is attributed to reductions in low birth weight and short gestational age
Synthesis of Research Evidence
ACCEPTABILITY
Data not found
FEASIBILITY
Intervention implemented although challenges with availability
FIDELITY
Low availability of magnesium at facilities with frequent stock outs
- Only 22% of facilities carried magnesium sulfate in 2014
- In 2016, 53% of facilities reported experiencing a stock out
High availability (92%) of antihypertensives at health facilities in 2016
2008 the national EmONC assessment found that anti-hypertensives were available at 75% of health centers and 99% and
in 2016 EmONC assessment showed better availability of anti-hypertensives, with drugs available at 92% of hospitals visited.
in 2016 the national EmONC assessment found stock-outs across all facility levels, primarily due to stock out at central or regional stores or inadequate transport of supplies.16
EFFECTIVENESS/REACH
High facility readiness (72%) but low provision (26% of facilities) of parenteral anticonvulsants with fairly low adherence to national guidelines - magnesium sulfate only used at 55% of hospitals that administered parenteral anticonvulsants in the 3 months preceding national EmONC survey in 2016
Provision of anti-hypertensives documented in less than half (48%) of pre-eclampsia and eclampsia cases assessed in 2016
Synthesis of Research Evidence
ACCEPTABILITY
High coverage suggested high acceptability- see effectiveness and coverage
FEASIBILITY
Immunization of 15 million women of childbearing age between 1999 and 2009
FIDELITY
Data not found
EFFECTIVENESS/REACH
Maternal and neonatal tetanus elimination achieved in all regions
High TT2 coverage achieved during supplemental immunization activities conducted in high-risk zones (76-94%)17
Elimination achieved and validated in 2017
The National Strategy for Newborn and Child Survival in Ethiopia (2015/16 – 2019/20) identified tetanus toxoid immunization during pregnancy as a high impact intervention for improving child survival. It set a coverage target of 90% of newborns protected against tetanus by 2020.
In 2017, all regions in the country were validated for maternal and neonatal tetanus elimination.18,19
Synthesis of Research Evidence
ACCEPTABILITY
Limited uptake of delivery services at facilities
Perceptions of institutional delivery remained negative
FEASIBILITY
By 2010, 33,819 HEWs had been trained and deployed and were estimated to reach 89% of communities
increase in number of trained midwives from 1,275 in 2008 to 9,244 in 2014
health centers (99%) and all hospital types (98%, 93%, 88% for primary, general, and referral hospitals, respectively
Increase in facilities providing delivery
Ambulances deployed across country
women believe that delivering at a health facility was:
- not necessary 42%,
- not customary 36%
- very costly 22%.20
FIDELITY
Policies enacted to reduce financial barriers to institutional delivery were not enforced. User fees for delivery services remained in place in many facilities21
EFFECTIVENESS/REACH
Some improvement in institutional delivery and assistance by a skilled provider per DHS
Per 2014 ESPA+, 99% of public facilities offered normal delivery services
26% of facilities charged a fee for normal delivery.21
In 2000:
- 32% in urban areas gave birth in a health facility, compared to only 2% in rural areas
- Those who live in Addis Ababa were most likely to deliver in a facility (67%), in Dire Dawa (31%), in Amhara (3%).
In 2016, proportions of facility-based over the previous five years vary widely by location, wealth, and urban/rural location delivery ranged from 14.7% in Afar to 97% in Addis Ababa22
Equity gap widened notably from 2000 to 2016 (IHME)
Synthesis of Research Evidence
ACCEPTABILITY
Data not found
FEASIBILITY
increased number of trained health workers
Improvement in proportion of UN-recommended standard number of EmONC facilities increased from 11% in 2008 to 40% in 2016
FIDELITY
Data not found
EFFECTIVENESS/REACH
Very low coverage of births taking place in BEmONC facilities
Estimated only 16% met need for BEmONC services in 2015
Geographic disparities in met BEmONC need
Synthesis of Research Evidence
ACCEPTABILITY
In 2016, low C-section national rates achieved at 3%, compared to the FMOH target of 7% by 2015.23
FEASIBILITY
High availability of C-section delivery in 2014 (77% in primary hospitals, 86% in general hospitals, 84% in referral hospitals)
Variable- rates remained low in many settings but higher in urban
FIDELITY
C-section national rates at 3% in 2016, (FMOH) or 1.9% (DHS) is very low due to low rates of facility-based deliveries compare to the FMOH target of 7% by 2015.23
Rate of 21.4% of C-sections in Addis Ababa suggest unnecessary C-section
EFFECTIVENESS/REACH
Deployment of 136 IESOs throughout Ethiopia and 462 in training in 201524
Increase in C-section rates in a few regions, per 2000 and 2016 DHS surveys but larger equity gap and decrease in some areas
Inequities in C-section rates between regions and urban/rural
In 2016 the equity gap has increased 10.6% of in urban versus 0.9% in rural
- 0.4% in the Somali
21.4% in Addis Ababa.
Synthesis of Research Evidence
ACCEPTABILITY
Data not found
FEASIBILITY
Expansion of CBNC to 70% of health posts nationally
FIDELITY
Uptake for deliveries remained < 100%
Limited improvement was seen in all clean cord care practices, with the exception of cutting the cord with a sterile instrument
Overall, 46% took clean cord care, compared to 36% at baseline.25
EFFECTIVENESS/REACH
Increase in clean delivery practices demonstrated by L10K program (46% vs 36% at baseline
Expansion to CBNC to 70% of health posts nationally
Limited progress seen in estimated mortality attributed to neonatal sepsis
Synthesis of Research Evidence
ACCEPTABILITY
Data not found
FEASIBILITY
Administered by few facilities at only at higher levels of care
FIDELITY
Stock outs
EFFECTIVENESS/REACH
National EmONC assessment in 2016 found only 9% of facilities had provided ACS over the previous three months
Availability of ACS at health facilities in 2016 varied by region – from 5% in Benishangul-Gumuz to 27% in Harari
Synthesis of Research Evidence
ACCEPTABILITY
Data not found
FEASIBILITY
Low levels of training in health providers in 2014
High availability of oxytocin
FIDELITY
Low correct usage (29%) of AMTSL observed in 2006 study
Lack of training – only 10% of providers interviewed in 2014 SPA+ received in-service training on AMTSL
EFFECTIVENESS/REACH
2006 study: low coverage of correct usage of AMSTL
Synthesis of Research Evidence
ACCEPTABILITY
Data not found
FEASIBILITY
Increased knowledge of providers
70% of facilities nationally staffed and equipped for neonatal resuscitation in 2016
FIDELITY
98% of facilities in 2016 had at least one staff member capable of providing neonatal resuscitation
Though data on quality of care was not found, a key informant noted “whenever we have a supportive supervision we collected some data and that data showed us good number of babies are salvaged and more than 90% are resuscitated and saved”
EFFECTIVENESS/REACH
Higher rates of neonatal resuscitation reported by key informant, but still low across regions per 2016 assessment16
Reach of training was limited (SPA 2014)
Regional differences in facility readiness to provide resuscitation
2016 EmONC assessment: resuscitation provided in highest percentage of facilities in Benishangul-Gumuz (88%) but lowest in Afar (42%)
Synthesis of Research Evidence
ACCEPTABILITY
Per KI, high willingness of facilities to prioritize establishment of NICUs and staff training due to prioritization by FMOH
FEASIBILITY
49% of NICUs functional by mid-2015
Challenge in lack of physical space at health facilities
FIDELITY
100% of target hospitals received NICU training by 2015
EFFECTIVENESS/REACH
Mid-2015, 49% of planned NICUs were operational in Ethiopia
Synthesis of Research Evidence
ACCEPTABILITY
High acceptability by mothers following education per KI:
“Mothers are very willing but they have fear. The fear is they think that they can kill their babies because babies are there when they sleep and they could suffocate their babies… In our case, we have counseling methods like videos, audios, and posters in Amharic and other local languages.”
FEASIBILITY
See coverage below
FIDELITY
Only 15% of providers surveyed in ESPA+ reported receiving in-service training on KMC
2014 assessment: only 14% of eligible neonates born in a facility offering KMC were actually enrolled
EFFECTIVENESS/REACH
2014 ESPA+: 67% of facilities providing normal delivery services offered KMC
Significant regional variation in availability of KMC at health facilities in 2014 - from only 2% of facilities in Afar to 84% in Benishangul-Gumuz26
Synthesis of Research Evidence
ACCEPTABILITY
Data not found
FEASIBILITY
Expansion of CBNC to 70% of health posts in the country by 2015
FIDELITY
Fairly low adherence to national treatment protocols in program midline assessment
EFFECTIVENESS/REACH
In program midline assessment, 94% of infants with very severe disease were given a pre-referral dose of antibiotics
Synthesis of Research Evidence
ACCEPTABILITY
Low uptake of PNC remains despite increased access through HEWs
Cultural beliefs and traditional practices such as the traditional 40-day confinement period intended to protect the mother and newborn from malevolent spirits limits care-seeking
FEASIBILITY
Expansion of PNC service delivery through HEP
FIDELITY
2016 DHS: only 27% of newborns born within the previous 2 years had at least 2 signal functions performed within 2 days after birth
EFFECTIVENESS/REACH
Coverage remains low – per 2012 DHS, 86% of newborns did not receive a post-natal check at any point after delivery
Lower coverage of postnatal checks for newborns who delivered outside of a health facility (1% vs 34% of those delivered in a facility), despite service delivery by HEWs to provide home-based care
Regional differences in coverage of postnatal checks within 2 days after delivery per 2016 DHS – ranging from 9% in Oromia to 55% in Addis Ababa
The primary research findings suggest additional contextual factors that contributed to U5M reductions in Ethiopia that were outside of the health system interventions. These include women’s empowerment, increased use of family planning and decreased fertility rates, improvements in water, sanitation and hygiene, and economic growth.
IHME DECOMPOSITION RESULTS
3% of the reduction in under-five mortality is attributed to improvements in WASH and air quality.1
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1
Gakidou, Emmanuela, et al. "Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016." The Lancet 390.10100 (2017): 1345-1422. Institute for Health Metrics and Evaluation (IHME). Seattle, WA: IHME; 2018.
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2
Amouzou, A, Surkan, P, and Shaw, Bryan. Determinants of Utilization of Health Extension Workers in the Context of Scale-up of Integrated Community Case Management of Childhood Illnesses in Ethiopia. American Journal of Tropical Medicine and Hygiene. 2015 Sep 2; 93(3): 636–647 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559711/. Accessed January 17, 2020.
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3
Integrated Community Case Management- iCCM/ Story in Ethiopia. Evidence Review Symposium. Accra, Ghana; 2014. https://www.childhealthtaskforce.org/sites/default/files/2019-07/iCCM%20Symposium%20Presentation_iCCM%20in%20Ethiopia%28MOH%20Ethiopia%2C%202014%29.pdf. Accessed January 5, 2020.
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4
World Health Organization (WHO). Ethiopia: WHO and UNICEF Estimates of Immunization Coverage: 2018 Revision. Geneva: WHO; 2019. http://www.who.int/immunization/monitoring_surveillance/data/eth.pdf. Accessed January 17, 2020.
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5
Abebe, A, Getahun, M, et al. Impact of rotavirus vaccine introduction and genotypic characteristics of rotavirus strains in children less than 5 years of age with gastroenteritis in Ethiopia: 2011–2016. Addis Ababa, Ethiopia: Vaccine; 2018. https://www.sciencedirect.com/science/article/pii/S0264410X18313173. Accessed January 17, 2020.
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6
World Health Organization (WHO). Ethiopia: WHO and UNICEF Estimates of Immunization Coverage: 2016 Revision. Geneva: WHO; 2017. https://data.unicef.org/wp-content/uploads/country_profiles/Ethiopia/immunization_country_profiles/immunization_eth.pdf. Accessed January 17, 2020.
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7
Proposal for Health Systems Strengthening (HSS) Cash Support. Ethiopia. https://www.gavi.org/country/ethiopia/documents/proposals/proposal-for-hss-support--ethiopia(2)/. Accessed January 17, 2020.
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8
Belete, Habtamu. (2016). Review on Measles Situation in Ethiopia; Past and Present. Journal of Tropical Diseases. 04. 10.4172/2329-891X.1000193. https://www.researchgate.net/publication/302915842_Review_on_Measles_Situation_in_Ethiopia_Past_and_Present. Accessed January 17, 2020.
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9
Federal Ministry of Health (FMOH) [Ethiopia]. MenA vaccine Introduction Country Experience, Ethiopia. Presented at: Closure Conference; February 22, 2016; Addis Ababa. https://www.who.int/immunization/research/meetings_workshops/Woldegiorgis_MVPconf16.pdf. Accessed January 17, 2020.
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10
Global Fund. Audit Report: Global Fund Grants to the Federal Democratic Republic of Ethiopia. Geneva, Switserland; 2017. https://www.theglobalfund.org/media/6981/oig_gf-oig-17-025_report_en.pdf?u=636637836220000000. Accessed December 1, 2019.
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11
Johns, B, Yihdego, Y et al. Indoor Residual Spraying Delivery Models to Prevent Malaria: Comparison of Community- and District-Based Approaches in Ethiopia. Global Health: Science and Practice Vol 4 Num 4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199172/pdf/529.pdf. Accessed January 17, 2020.
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12
Federal Ministry of Health (FMOH) [Ethiopia]. Health Sector Transformation Plan-I Annual Performance Report. Addis Ababa: FMOH; 2017. https://www.itacaddis.org/docs/2017_11_10_09_48_31_ARM%202017.compressed.pdf. Accessed January 17, 2020.
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13
Ethiopia: HIV Country Profile: 2016. World Health Organization. WHO/HIV/2017.59 https://www.who.int/hiv/data/Country_profile_Ethiopia.pdf?ua=1. Accessed January 17, 2020.
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14
Kassa GM. Mother-to-child transmission of HIV infection and its associated factors in Ethiopia: a systematic review and meta-analysis. BMC Infect Dis. 2018;18(1):216. https://doi.org/10.1186/s12879-018-3126-5. Accessed January 17, 2020.
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15
Tadesse E, Worku A, Berhane Y, Ekström EC. An integrated community-based outpatient therapeutic feeding programme for severe acute malnutrition in rural Southern Ethiopia: Recovery, fatality, and nutritional status after discharge. Matern Child Nutr. 2018;14(2):e12519. https://doi.org/10.1111/mcn.12519. Accessed January 17, 2020.
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16
Ethiopian Public Health Institute (EPHI), Federal Ministry of Health (FMOH) [Ethiopia], and Averting Maternal Death and Disability (AMDD)/Columbia University. Ethiopian Emergency Obstetric and Newborn Care (EmONC) Assessment 2016: Final Report. Addis Ababa and New York: EPHI, FMOH, and AMDD; 2017. https://www.ephi.gov.et/images/pictures/download2010/FINAL-EmONC-Final-Report-Oct25-2017.pdf. Accessed January 17, 2020.
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17
Federal Ministry of Health (FMOH) [Ethiopia]. Ethiopia National Expanded Programme on Immunization: Comprehensive Multi-year plan 2011-2015. Addis Ababa: FMOH; 2010. https://bidinitiative.org/wp-content/files_mf/1405630243EthiopiaComprehensivemultiyearplanfor20112015Year2010.pdf. Accessed January 17, 2020 .
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18
Ethiopia attains maternal and neonatal tetanus elimination. United Nations Children’s Fund (UNICEF) Ethiopia blog. https://reliefweb.int/report/ethiopia/ethiopia-attains-maternal-and-neonatal-tetanus-elimination. Published June 30, 2017. Accessed January 17, 2020.
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19
Maternal and neonatal tetanus elimination (MNTE). World Health Organization (WHO) website. https://www.who.int/immunization/diseases/MNTE_initiative/en/index2.html. Updated December 16, 2019. Accessed January 17, 2020.
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20
Shiferaw, S, Spigt, M et al. Why do women prefer home births in Ethiopia? BMC Pregnancy and Childbirth 2013, 13:5. https://bmcpregnancychildbirth.biomedcentral.com/track/pdf/10.1186/1471-2393-13-5. Accessed January 17, 2020.
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21
Pearson L, Gandhi M, Admasu K, Keyes EB. User fees and maternity services in Ethiopia. Int J Gynaecol Obstet. 2011;115(3):310–315. https://doi.org/10.1016/j.ijgo.2011.09.007. Accessed January 17, 2020.
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22
ICF. Place of delivery: health facility, by region, residence, and wealth quintile – Ethiopia [data set]. STATcompiler. Rockville, MD: The Demographic and Health Surveys (DHS) Program. Fairfax, VA: ICF; 2012. http://www.statcompiler.com. Accessed December 12, 2019.
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23
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